Newer Therapies In Management of Neonatal Birth Asphyxia

Current Controversies in Newer Therapies to Treat Birth Asphyxia

Despite major advances in monitoring technology and knowledge of fetal and neonatal pathophysiology, neonatal hypoxic-ischemic encephalopathy (HIE) remains one of the main causes of severe adverse neurological outcome in children. Until recently, there were no therapies other than supportive measures. Over the past several years, mild hypothermia has been proven to be safe to treat HIE. Unfortu...

Birth asphyxia, Apgar score and neonatal encephalopathy.

As infant mortality rates decline steadily in South Asia, largely through a fall in post-neonatal mortality, increasing attention is turning to the perinatal period(l). Many studies in this region have demonstrated birth asphyxia to be a major cause of perinatal death(2). However, the contribution of birth asphyxia to the burden of neurodisability in developing country populations is still to b...

Birth asphyxia.

Newer Therapies in COPD

Chronic Obstructive Pulmonary Disease (COPD), a common preventable and treatable disease, is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Exacerbations and comorbidities contribute significantly to the overall severity in individual patients. COP...

Therapeutic hypothermia in neonatal asphyxia

Hypoxic ischemic encephalopathy is a serious condition affecting newborn infants which can result in death and disability. There is now strong clinical evidence that moderate post-asphyxial total body cooling or hypothermia in full term neonates results in long-term neuroprotection, allowing us to proclaim this innovative therapy as "standard of care." The treatment is a time-critical emergency...